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    27 repositories

    • SLiM

      Public
      SLiM is a genetically explicit forward simulation software package for population genetics and evolutionary biology. It is highly flexible, with a built-in scr…
      slim
      slim
      C++
      •
      GNU General Public License v3.0
      •38•233•35•6•Updated Oct 1, 2026Oct 1, 2026

    • SLiM6Paper

      Public
      Scripts and data for our paper about SLiM 6.0
      R
      •
      MIT License
      •0•0•0•0•Updated Sep 30, 2026Sep 30, 2026

    • SLiM-Tests

      Public
      Additional tests for SLiM validation and performance evaluation
      slim
      slim
      Slim
      •1•0•0•0•Updated Sep 26, 2026Sep 26, 2026

    • MultispeciesGeneDriveNZ

      Public
      Code for the forthcoming "Evaluating Gene Drive for Invasive Mammal Control in a Complex Ecological Model of the South Island of New Zealand".
      Slim
      •0•0•0•0•Updated Sep 11, 2026Sep 11, 2026

    • multilocus-suppression

      Public
      R
      •0•0•0•0•Updated Jul 24, 2026Jul 24, 2026

    • SLiM5Paper

      Public
      Scripts and data for our paper about SLiM 5.0.
      Slim
      •
      MIT License
      •0•0•0•0•Updated Jan 22, 2026Jan 22, 2026

    • Containment

      Public
      Code and data for "Predicting the invasiveness of threshold-dependent gene drives" paper
      R
      •0•0•0•0•Updated Nov 9, 2025Nov 9, 2025

    • SLiM-Extras

      Public
      Extra add-ons that may be useful for people using SLiM, but that are not part of the SLiM project itself
      slim
      slim
      Jupyter Notebook
      •16•45•0•1•Updated Oct 30, 2025Oct 30, 2025

    • ResourceExplicitModels

      Public
      Models and data for "Resource-Explicit Interaction Models for Spatial Populations"
      Slim
      •0•6•0•0•Updated Apr 14, 2025Apr 14, 2025

    • cluster-guide

      Public
      Slim
      •0•1•0•0•Updated Dec 5, 2023Dec 5, 2023

    • SLiM-Benchmarks

      Public
      Benchmarking scripts to compare single-threaded and multi-threaded SLiM performance
      slim
      slim
      Slim
      •1•1•0•0•Updated Aug 14, 2023Aug 14, 2023

    • Chasing

      Public
      Data and models for "Suppression gene drive in continuous space can result in unstable persistence of both drive and wild-type alleles"
      Slim
      •0•1•0•0•Updated Jan 23, 2023Jan 23, 2023

    • CRISPR-Cas9-fitness-effects

      Public
      Files and data to accompany "Fitness effects of CRISPR endonucleases in D. melanogaster populations"
      R
      •
      Other
      •0•0•0•0•Updated Sep 30, 2022Sep 30, 2022

    • PerformanceOfAnophelesDriveCandidates

      Public
      Models and data to accompany "Finding the strongest gene drive: Simulations reveal unexpected performance differences between Anopheles homing suppression drive…
      Slim
      •0•1•0•0•Updated Apr 8, 2022Apr 8, 2022

    • TetheredDrives

      Public
      Data and code for "Experimental demonstration of tethered gene drive systems for confined population modification or suppression."
      Mathematica
      •0•0•0•0•Updated Apr 7, 2022Apr 7, 2022

    • HomingSuppressionDrive

      Public
      Data and code for "A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles."
      R
      •1•0•0•0•Updated Dec 25, 2021Dec 25, 2021

    • GeneDriveForSuppressionOfInvasiveRodents

      Public
      Files and data to accompany "Modeling CRISPR gene drives for suppression of invasive rodents".
      Python
      •1•3•0•0•Updated Oct 7, 2021Oct 7, 2021

    • evolve-resequence-simulation

      Public
      A customizable tool for simulation of evolve and resequence experiments on a quantitative trait
      R
      •3•2•0•0•Updated Jun 16, 2021Jun 16, 2021

    • GeneDriveForRodentControl

      Public
      Files and data to accompany "Modeling the potential of CRISPR gene drives for rodent management".
      0•0•0•0•Updated Oct 16, 2020Oct 16, 2020

    • HaplolethalHomingDrive

      Public
      Files associated with "A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population".
      1•0•0•0•Updated Aug 7, 2020Aug 7, 2020

    • asymptoticMK

      Public
      A web-based tool for estimating alpha, the fraction of nucleotide substitutions in a given genomic region that were driven to fixation by positive selection.
      R
      •
      GNU General Public License v3.0
      •1•6•1•0•Updated Jan 20, 2020Jan 20, 2020

    • Binomial-Analysis

      Public
      A tool for performing binomial analysis to detect batch effects
      R
      •1•0•0•0•Updated Dec 29, 2019Dec 29, 2019

    • TA-Underdominance-Drives

      Public
      Models and data for "Design and analysis of CRISPR-based underdominance toxin-antidote gene drives."
      HTML
      •0•0•0•0•Updated Dec 4, 2019Dec 4, 2019

    • ToxinAntidoteSystems

      Public
      Data and code for "Performance analysis of novel toxin-antidote CRISPR gene drive systems"
      HTML
      •0•0•0•0•Updated Nov 11, 2019Nov 11, 2019

    • Homing_Mechanisms_with_multiplexed_gRNAs

      Public
      Data and models for "Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs"
      HTML
      •0•0•0•0•Updated Oct 30, 2019Oct 30, 2019

    • UnderdominanceGeneDriveSystems

      Public
      Models and data for "Population dynamics of underdominance gene drive systems in continuous space."
      HTML
      •0•0•0•0•Updated Oct 2, 2019Oct 2, 2019

    • ResistanceInGeneDrives

      Public
      HTML
      •0•0•0•0•Updated Feb 21, 2018Feb 21, 2018
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