library of C++ functions that support applications of Stan in Pharmacometrics

Population Experimental Design (PopED) in R

Chi is an open source Python package which is designed for PKPD modelling and model-informed precision dosing (MIPD).

R package for using ubiquity

PySB add-on providing domain-specific macros and models for empirical and mechanistic PK/PD modeling.

Create diagrams with ggplot.

Physiology-based systems pharmacology model of thyroid hormones regulation in rat and human

Open Python Web App for Pharmcological Modeling and Analysis

How to cite: Van De Vyver, A.J., Eigenmann, M.J., Ovacik, M., Pöhl, C., Herter, S., Weinzierl, T., Fauti, T., Klein, C., Lehr, T., Bacac, M., Walz, A.-C. (2021). A novel approach for quantifying the pharmacological activity of T cell engagers utilizing in vitro time course experiments and streamlined data analysis. AAPS

ODE-based quantitative systems pharmacology model of B cell depletion and repopulation under anti-CD20 therapy (rituximab, ocrelizumab). Multi-compartment PK/PD with Bayesian parameter estimation, uncertainty quantification, and posterior predictive validation. Python · PyMC · scipy · MLflow.

PK/PD clinical trial simulator with virtual patients, adaptive randomization, external-control borrowing, and protocol optimization.

Physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model of canagliflozin

Reproducibility-first mechanistic biology research stack: CFM (SCNT feasibility), BSE (virtual PK/PD physiology), and NSCS (closed-loop equation discovery).

R client to the Rx Studio APIs.

Interactive PK/PD simulator for 18 hospital antimicrobials — educational tool for dose optimization

Semi-mechanistic PK/PD model of radioligand therapy implemented in PySB with pysb-pkpd and pysb-units.

MATLAB and Python (Google Colab-oriented) pharmacokinetic models

Python-first toolkit for dissolution similarity, NCA, PK/PD simulation, and pharmacometric reporting