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Add BioMCP — 27-tool bioinformatics MCP server - #3731

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Add BioMCP — 27-tool bioinformatics MCP server#3731
SachinGawande2003 wants to merge 1 commit into
modelcontextprotocol:mainfrom
SachinGawande2003:main

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@SachinGawande2003

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BioMCP — Bioinformatics Model Context Protocol Server

GitHub: https://github.com/SachinGawande2003/biomcp

What is BioMCP?

BioMCP connects Claude to every major biological database and
state-of-the-art AI models through MCP. Researchers can search
PubMed, predict protein structures, find drug targets, query
clinical trials, and generate DNA sequences — all in natural
language.

Tools (27 total across 6 categories)

  • 📚 Literature & NCBI — PubMed, Gene lookup, BLAST
  • 🧪 Proteins & Structures — UniProt, AlphaFold, RCSB PDB
  • 🔬 Pathways — KEGG, Reactome
  • 💊 Drug Discovery — ChEMBL, Open Targets
  • 🏥 Clinical — ClinicalTrials.gov
  • 🤖 AI Models (NVIDIA NIM) — MIT Boltz-2, Arc Evo2-40B

Databases (16 total)

PubMed · NCBI Gene · BLAST · UniProt · AlphaFold DB ·
RCSB PDB · KEGG · Reactome · ChEMBL · Open Targets ·
Ensembl · ClinicalTrials.gov · Human Cell Atlas ·
NCBI GEO · OpenNeuro · NeuroVault

Key Features

  • Async-first, fully non-blocking
  • Rate limiting + TTL caching per API
  • Exponential backoff retry logic
  • Input validation before any network call
  • Flagship multi-omics tool queries 7 databases in parallel

Installation

pip install biomcp

License

MIT

@olaservo

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Thanks for contributing to the MCP servers repo!

We've retired the third-party server list from the README in favor of the MCP Registry — see #3950 for context. The Official Integrations and Community Servers sections no longer exist in the README, so this PR no longer has a target.

Going forward, please publish your server to the MCP Registry using the quickstart guide:
https://github.com/modelcontextprotocol/registry/blob/main/docs/modelcontextprotocol-io/quickstart.mdx

That's where server discovery now happens. Thanks for building on MCP!


Note: I'm working through the backlog with help from Claude Code to give everyone a prompt response.

@olaservo olaservo closed this Apr 14, 2026
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