Welcome to the VU Bioinformatics Group!

We aim to understand biological processes across different levels of molecular and cellular organisation. By combining advanced computational analysis with state-of-the-art modelling techniques, we investigate protein structure, complex biological datasets and networks to uncover the mechanisms that shape health and disease.

Our research focuses on three broad areas.

We develop computational approaches to study:

• Protein structure and function
• Protein–protein interactions
• Molecular properties and interactions

We develop and apply methods for:

• Sequence analysis and alignment
• Single-cell protein quantification technologies
• FAIR data stewardship
• Computational and statistical methods development

We are embedded in the Department of Computer Science at Vrije Universiteit Amsterdam.

Explore some of our research software, datasets, and computational methods:

• PRALINE — Brief description of the project.
• PIPENN — Brief description of the project.
• Project name — Brief description of the project.

See all our repositories in the Repositories tab above.

We contribute to the joint-degree (with Universiteit van Amsterdam) Master's programme in Bioinformatics and Systems Biology.

The programme is organised jointly by:

• The Bioinformatics Group at Vrije Universiteit Amsterdam
• The Systems Biology Lab at Vrije Universiteit Amsterdam
• The Swammerdam Institute for Life Sciences (Biosystems Data Analysis) at the University of Amsterdam

The programme combines bioinformatics, systems biology, computer science, statistics, and molecular biology to prepare students for research at the interface of biology and computation.

➡️ Learn more about the Bioinformatics and Systems Biology Master's programme

Our group teaches the following courses as part of the Master's program - Fundamentals of Bioinformatics, Algorithms in Sequence Analysis, Structural Bioinformatics, Scientific Machine Learning and Bioinformatics in Translational Medicine.

The VU Bioinformatics Group works closely with researchers from several academic, clinical, and research institutions, including:

• Amsterdam UMC
• Amsterdam Institute of Molecular and Life Sciences – AIMMS
• University of Amsterdam
• Netherlands Cancer Institute – NKI
• Centrum Wiskunde & Informatica – CWI

These collaborations support interdisciplinary research connecting computational method development with fundamental biology and clinical applications.

Our repositories may contain:

• Bioinformatics software and libraries
• Sequence-analysis tools
• Protein-modelling methods
• Data-processing pipelines
• Research datasets
• Tutorials and teaching materials
• Code associated with scientific publications

Please consult the individual repository README files for installation instructions, documentation, licences, citation information, and project status.

For more information about our research, teaching, publications, and group members, visit the VU Bioinformatics Group website. For queries about github reach out to Rachit Kumar (r.kumar@vu.nl)

Vrije Universiteit Amsterdam Department of Computer Science Amsterdam, the Netherlands