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nextflow-variant-calling

This is a GATK based variant calling workflow written in Nextflow.

The workflow is contained in the main.nf script.

The workflow has the following inputs:

  • reference genome, indexed with bwa index: the path to the FASTA file (local or S3) can be given in the "--ref" commandline option
  • sample sheet CSV file with header "sample,fastq_1,fastq_2"

Example sample sheets are included.

To run the workflow, please modify run-ec2-test.sh or run-local-test.sh with paths to your data

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