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1. Causal-deep-learning-GNN-multi-omic Causal-deep-learning-GNN-multi-omic Public

   Causally-anchored multi-omic deep learning that recovers exercise-responsive and ageing-causal genes from human physical activity. LD-aware multi-omic Mendelian randomisation + graph-attention netw…

   R

2. protein-ligand-binding-affinity-ageing-targets protein-ligand-binding-affinity-ageing-targets Public

   Leakage-aware ML pipeline predicting protein-ligand binding affinity for ageing-nominated targets: ChEMBL + BindingDB harmonisation, scaffold/cluster/temporal splits, explicit leakage audit, and co…

   Python

3. protobind-ctsf-generative-triage protobind-ctsf-generative-triage Public

   Target-conditioned ligand generation with Gero's ProtoBind-Diff diffusion model, with leakage-aware, novelty-filtered triage. Honest scope: candidates, not validated binders.

   Jupyter Notebook

4. quercetin-ADMET-permeability quercetin-ADMET-permeability Public

   In silico ADMET permeability analysis of quercetin and its circulating human metabolites comparing intestinal absorption and passive permeation potential of the aglycone vs its glucuronide, sulfate…

   Python 1

5. rag-pipeline-grounded-llm-genomics rag-pipeline-grounded-llm-genomics Public

   LLM · RAG · MCP: a retrieval-augmented pipeline that answers questions over my ageing & exercise genomics research from papers and gene-level results, with cited, grounded answers, plus an MCP serv…

   Python

6. LD-aware-overlap-aware-MR-for-the-effects-of-UKBB-vigorous-activity-on-UKBB-plasma-proteomics LD-aware-overlap-aware-MR-for-the-effects-of-UKBB-vigorous-activity-on-UKBB-plasma-proteomics Public

   LD-aware, overlap-aware Mendelian randomisation of UK Biobank vigorous activity on plasma proteomics.

   R