diff --git a/CHANGELOG.md b/CHANGELOG.md
index f5ecc509c3c4..cf5ebd5fdb6d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,7 +7,9 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased]
 
-- Nothing yet!
+### Fixed
+
+- Remove deprecation warnings by using `Module#registerHooks` instead of `Module#register` on Node 26+ ([#20028](https://github.com/tailwindlabs/tailwindcss/pull/20028))
 
 ## [4.3.0] - 2026-05-08
 
diff --git a/packages/@tailwindcss-node/src/esm-cache.loader.mts b/packages/@tailwindcss-node/src/esm-cache.loader.mts
index edcfc8d778ba..952b2f189d94 100644
--- a/packages/@tailwindcss-node/src/esm-cache.loader.mts
+++ b/packages/@tailwindcss-node/src/esm-cache.loader.mts
@@ -1,8 +1,22 @@
-import { isBuiltin, type ResolveHook } from 'node:module'
+import {
+  isBuiltin,
+  type ResolveFnOutput,
+  type ResolveHook,
+  type ResolveHookContext,
+  type ResolveHookSync,
+} from 'node:module'
 
 export let resolve: ResolveHook = async (specifier, context, nextResolve) => {
   let result = await nextResolve(specifier, context)
+  return processResolve(context, result)
+}
+
+export let resolveSync: ResolveHookSync = (specifier, context, nextResolve) => {
+  let result = nextResolve(specifier, context)
+  return processResolve(context, result)
+}
 
+function processResolve(context: ResolveHookContext, result: ResolveFnOutput) {
   if (result.url === import.meta.url) return result
   if (isBuiltin(result.url)) return result
   if (!context.parentURL) return result
diff --git a/packages/@tailwindcss-node/src/index.cts b/packages/@tailwindcss-node/src/index.cts
index 4bca0a5e11de..9f27889337d3 100644
--- a/packages/@tailwindcss-node/src/index.cts
+++ b/packages/@tailwindcss-node/src/index.cts
@@ -1,6 +1,7 @@
 import * as Module from 'node:module'
 import { pathToFileURL } from 'node:url'
 import * as env from './env'
+import { resolveSync } from './esm-cache.loader.mjs'
 export * from './compile'
 export * from './instrumentation'
 export * from './normalize-path'
@@ -12,8 +13,14 @@ export { env }
 // not necessary.
 if (!process.versions.bun) {
   // `Module#register` was added in Node v18.19.0 and v20.6.0
+  // `Module#registerHooks` was added in Node v22.15.0 and v23.5.0 and is the preferred API since v25.9.0,
+  // runtime-deprecating `Module#register` since v26
   //
   // Not calling it means that while ESM dependencies don't get reloaded, the
   // actual included files will because they cache bust directly via `?id=…`
-  Module.register?.(pathToFileURL(require.resolve('@tailwindcss/node/esm-cache-loader')))
+  if (Module.registerHooks) {
+    Module.registerHooks({ resolve: resolveSync })
+  } else {
+    Module.register?.(pathToFileURL(require.resolve('@tailwindcss/node/esm-cache-loader')))
+  }
 }
diff --git a/packages/@tailwindcss-node/src/index.ts b/packages/@tailwindcss-node/src/index.ts
index a5e7bf5b4bc3..22a62b248937 100644
--- a/packages/@tailwindcss-node/src/index.ts
+++ b/packages/@tailwindcss-node/src/index.ts
@@ -1,6 +1,7 @@
 import * as Module from 'node:module'
 import { pathToFileURL } from 'node:url'
 import * as env from './env'
+import { resolveSync } from './esm-cache.loader.mjs'
 export * from './compile'
 export * from './instrumentation'
 export * from './normalize-path'
@@ -14,8 +15,14 @@ if (!process.versions.bun) {
   let localRequire = Module.createRequire(import.meta.url)
 
   // `Module#register` was added in Node v18.19.0 and v20.6.0
+  // `Module#registerHooks` was added in Node v22.15.0 and v23.5.0 and is the preferred API since v25.9.0,
+  // runtime-deprecating `Module#register` since v26
   //
   // Not calling it means that while ESM dependencies don't get reloaded, the
   // actual included files will because they cache bust directly via `?id=…`
-  Module.register?.(pathToFileURL(localRequire.resolve('@tailwindcss/node/esm-cache-loader')))
+  if (Module.registerHooks) {
+    Module.registerHooks({ resolve: resolveSync })
+  } else {
+    Module.register?.(pathToFileURL(localRequire.resolve('@tailwindcss/node/esm-cache-loader')))
+  }
 }