diff --git a/compiler/rustc/Cargo.toml b/compiler/rustc/Cargo.toml
index 8cef9e0644bb0..e3e94e440f694 100644
--- a/compiler/rustc/Cargo.toml
+++ b/compiler/rustc/Cargo.toml
@@ -37,7 +37,6 @@ features = ['override_allocator_on_supported_platforms']
 check_only = ['rustc_driver_impl/check_only']
 jemalloc = ['dep:tikv-jemalloc-sys']
 llvm = ['rustc_driver_impl/llvm']
-llvm_enzyme = ['rustc_driver_impl/llvm_enzyme']
 llvm_offload = ['rustc_driver_impl/llvm_offload']
 max_level_info = ['rustc_driver_impl/max_level_info']
 rustc_randomized_layouts = ['rustc_driver_impl/rustc_randomized_layouts']
diff --git a/compiler/rustc_builtin_macros/Cargo.toml b/compiler/rustc_builtin_macros/Cargo.toml
index f5dbc4a0d7cbe..59f00728f7fda 100644
--- a/compiler/rustc_builtin_macros/Cargo.toml
+++ b/compiler/rustc_builtin_macros/Cargo.toml
@@ -35,5 +35,4 @@ tracing = "0.1"
 
 [features]
 # tidy-alphabetical-start
-llvm_enzyme = []
 # tidy-alphabetical-end
diff --git a/compiler/rustc_codegen_llvm/Cargo.toml b/compiler/rustc_codegen_llvm/Cargo.toml
index ec850cf7ab3d2..6680d1323a923 100644
--- a/compiler/rustc_codegen_llvm/Cargo.toml
+++ b/compiler/rustc_codegen_llvm/Cargo.toml
@@ -43,7 +43,6 @@ tracing = "0.1"
 [features]
 # tidy-alphabetical-start
 check_only = ["rustc_llvm/check_only"]
-llvm_enzyme = []
 llvm_offload = []
 # tidy-alphabetical-end
 
diff --git a/compiler/rustc_codegen_llvm/src/back/lto.rs b/compiler/rustc_codegen_llvm/src/back/lto.rs
index b2d22876c1858..70d48def59e91 100644
--- a/compiler/rustc_codegen_llvm/src/back/lto.rs
+++ b/compiler/rustc_codegen_llvm/src/back/lto.rs
@@ -617,7 +617,7 @@ pub(crate) fn run_pass_manager(
         );
     }
 
-    if cfg!(feature = "llvm_enzyme") && enable_ad && !thin {
+    if enable_ad && !thin {
         let opt_stage = llvm::OptStage::FatLTO;
         let stage = write::AutodiffStage::PostAD;
         if !config.autodiff.contains(&config::AutoDiff::NoPostopt)
diff --git a/compiler/rustc_codegen_llvm/src/typetree.rs b/compiler/rustc_codegen_llvm/src/typetree.rs
index 7c2e09227e46b..9988ccfaee052 100644
--- a/compiler/rustc_codegen_llvm/src/typetree.rs
+++ b/compiler/rustc_codegen_llvm/src/typetree.rs
@@ -75,15 +75,9 @@ enum TTLocation {
     Callsite,
 }
 
-#[cfg_attr(not(feature = "llvm_enzyme"), allow(unused))]
 pub(crate) fn add_tt<'tcx, 'll>(cx: &FullCx<'ll, 'tcx>, fn_def: &'ll Value, tt: FncTree) {
-    // TypeTree processing uses functions from Enzyme, which we might not have available if we did
-    // not build this compiler with `llvm_enzyme`. This feature is not strictly necessary, but
-    // skipping this function increases the chance that Enzyme fails to compile some code.
-    // FIXME(autodiff): In the future we should conditionally run this function even without the
-    // `llvm_enzyme` feature, in case that libEnzyme was provided via rustup.
-    #[cfg(not(feature = "llvm_enzyme"))]
-    return;
+    // TypeTree processing uses functions from Enzyme. This feature is not strictly necessary,
+    // but skipping this function increases the chance that Enzyme fails to compile some code.
 
     let tcx = cx.tcx;
     if !tcx.sess.opts.unstable_opts.autodiff.contains(&rustc_session::config::AutoDiff::Enable) {
diff --git a/compiler/rustc_driver_impl/Cargo.toml b/compiler/rustc_driver_impl/Cargo.toml
index aeb2063e76960..c7d3e4fae3fc5 100644
--- a/compiler/rustc_driver_impl/Cargo.toml
+++ b/compiler/rustc_driver_impl/Cargo.toml
@@ -58,7 +58,6 @@ ctrlc = "3.4.4"
 # tidy-alphabetical-start
 check_only = ['rustc_interface/check_only']
 llvm = ['rustc_interface/llvm']
-llvm_enzyme = ['rustc_interface/llvm_enzyme']
 llvm_offload = ['rustc_interface/llvm_offload']
 max_level_info = ['rustc_log/max_level_info']
 rustc_randomized_layouts = [
diff --git a/compiler/rustc_interface/Cargo.toml b/compiler/rustc_interface/Cargo.toml
index 9c115736a3d4f..4a272867046b4 100644
--- a/compiler/rustc_interface/Cargo.toml
+++ b/compiler/rustc_interface/Cargo.toml
@@ -57,6 +57,5 @@ rustc_abi = { path = "../rustc_abi" }
 # tidy-alphabetical-start
 check_only = ['rustc_codegen_llvm?/check_only']
 llvm = ['dep:rustc_codegen_llvm']
-llvm_enzyme = ['rustc_builtin_macros/llvm_enzyme', 'rustc_codegen_llvm/llvm_enzyme']
 llvm_offload = ['rustc_codegen_llvm/llvm_offload']
 # tidy-alphabetical-end
diff --git a/library/core/Cargo.toml b/library/core/Cargo.toml
index 5421b1d2a2652..3f5f9f454a99d 100644
--- a/library/core/Cargo.toml
+++ b/library/core/Cargo.toml
@@ -23,7 +23,6 @@ optimize_for_size = []
 # Make `RefCell` store additional debugging information, which is printed out when
 # a borrow error occurs
 debug_refcell = []
-llvm_enzyme = []
 
 [lints.rust.unexpected_cfgs]
 level = "warn"
@@ -39,7 +38,6 @@ check-cfg = [
     'cfg(target_has_reliable_f16_math)',
     'cfg(target_has_reliable_f128)',
     'cfg(target_has_reliable_f128_math)',
-    'cfg(llvm_enzyme)',
     # Prevents use of a static variable for providing platform specific RawOsError
     # functionality
     'cfg(no_io_statics)',
diff --git a/library/std/Cargo.toml b/library/std/Cargo.toml
index 4c433d4970cda..0ee89dee4d7fc 100644
--- a/library/std/Cargo.toml
+++ b/library/std/Cargo.toml
@@ -125,8 +125,6 @@ optimize_for_size = ["core/optimize_for_size", "alloc/optimize_for_size"]
 # a borrow error occurs
 debug_refcell = ["core/debug_refcell"]
 
-llvm_enzyme = ["core/llvm_enzyme"]
-
 # Enable using raw-dylib for Windows imports.
 # This will eventually be the default.
 windows_raw_dylib = ["windows-link/windows_raw_dylib"]
diff --git a/library/sysroot/Cargo.toml b/library/sysroot/Cargo.toml
index b2069ef6a613b..10562389d62d3 100644
--- a/library/sysroot/Cargo.toml
+++ b/library/sysroot/Cargo.toml
@@ -32,4 +32,3 @@ optimize_for_size = ["std/optimize_for_size"]
 panic-unwind = ["std/panic-unwind"]
 profiler = ["dep:profiler_builtins"]
 windows_raw_dylib = ["std/windows_raw_dylib"]
-llvm_enzyme = ["std/llvm_enzyme"]
diff --git a/src/bootstrap/src/lib.rs b/src/bootstrap/src/lib.rs
index 2c8e002123abf..e2710b4d7621c 100644
--- a/src/bootstrap/src/lib.rs
+++ b/src/bootstrap/src/lib.rs
@@ -849,9 +849,9 @@ impl Build {
             features.insert("compiler-builtins-mem");
         }
 
-        if self.config.llvm_enzyme {
-            features.insert("llvm_enzyme");
-        }
+        //if self.config.llvm_enzyme {
+        //    features.insert("llvm_enzyme");
+        //}
 
         features.into_iter().collect::<Vec<_>>().join(" ")
     }
@@ -873,9 +873,9 @@ impl Build {
         if (self.config.llvm_enabled(target) || kind == Kind::Check) && check("llvm") {
             features.push("llvm");
         }
-        if self.config.llvm_enzyme {
-            features.push("llvm_enzyme");
-        }
+        //if self.config.llvm_enzyme {
+        //    features.push("llvm_enzyme");
+        //}
         if self.config.llvm_offload {
             features.push("llvm_offload");
         }