diff --git a/instrumentation/opentelemetry-instrumentation-pymysql/src/opentelemetry/instrumentation/pymysql/__init__.py b/instrumentation/opentelemetry-instrumentation-pymysql/src/opentelemetry/instrumentation/pymysql/__init__.py
index 0b9eb4b3b9..99afe5e52e 100644
--- a/instrumentation/opentelemetry-instrumentation-pymysql/src/opentelemetry/instrumentation/pymysql/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-pymysql/src/opentelemetry/instrumentation/pymysql/__init__.py
@@ -142,6 +142,19 @@
 Warning:
     Capture of sqlcomment in ``db.statement``/``db.query.text`` may have high cardinality without platform normalization. See `Semantic Conventions for database spans <https://opentelemetry.io/docs/specs/semconv/database/database-spans/#generating-a-summary-of-the-query-text>`_ for more information.
 
+Capture parameters
+******************
+By default, only statements are captured, without the associated query parameters.
+To capture query parameters, enable ``capture_parameters``.
+
+.. code:: python
+
+    from opentelemetry.instrumentation.pymysql import PyMySQLInstrumentor
+
+    PyMySQLInstrumentor().instrument(
+        capture_parameters=True,
+    )
+
 API
 ---
 """
@@ -178,6 +191,7 @@ def _instrument(self, **kwargs):  # pylint: disable=no-self-use
         enable_attribute_commenter = kwargs.get(
             "enable_attribute_commenter", False
         )
+        capture_parameters = kwargs.get("capture_parameters", False)
 
         dbapi.wrap_connect(
             __name__,
@@ -190,6 +204,7 @@ def _instrument(self, **kwargs):  # pylint: disable=no-self-use
             enable_commenter=enable_sqlcommenter,
             commenter_options=commenter_options,
             enable_attribute_commenter=enable_attribute_commenter,
+            capture_parameters=capture_parameters,
         )
 
     def _uninstrument(self, **kwargs):  # pylint: disable=no-self-use
@@ -203,6 +218,7 @@ def instrument_connection(
         enable_commenter=None,
         commenter_options=None,
         enable_attribute_commenter=None,
+        capture_parameters=False,
     ):
         """Enable instrumentation in a PyMySQL connection.
 
@@ -221,6 +237,8 @@ def instrument_connection(
                 You can specify various options, such as enabling driver information, database version logging,
                 traceparent propagation, and other customizable metadata enhancements.
                 See *SQLCommenter Configurations* above for more information.
+            capture_parameters:
+                A flag to enable query parameter capture.
         Returns:
             An instrumented connection.
         """
@@ -236,6 +254,7 @@ def instrument_connection(
             commenter_options=commenter_options,
             connect_module=pymysql,
             enable_attribute_commenter=enable_attribute_commenter,
+            capture_parameters=capture_parameters,
         )
 
     @staticmethod
diff --git a/instrumentation/opentelemetry-instrumentation-pymysql/tests/test_pymysql_integration.py b/instrumentation/opentelemetry-instrumentation-pymysql/tests/test_pymysql_integration.py
index 2abfbbe97f..d21b519930 100644
--- a/instrumentation/opentelemetry-instrumentation-pymysql/tests/test_pymysql_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-pymysql/tests/test_pymysql_integration.py
@@ -118,6 +118,7 @@ def test_instrument_connection_enable_commenter_dbapi_kwargs(
             enable_commenter=True,
             commenter_options={"foo": True},
             enable_attribute_commenter=True,
+            capture_parameters=True,
         )
         cursor = cnx.cursor()
         cursor.execute("SELECT * FROM test")
@@ -125,6 +126,21 @@ def test_instrument_connection_enable_commenter_dbapi_kwargs(
         self.assertEqual(kwargs["enable_commenter"], True)
         self.assertEqual(kwargs["commenter_options"], {"foo": True})
         self.assertEqual(kwargs["enable_attribute_commenter"], True)
+        self.assertEqual(kwargs["capture_parameters"], True)
+
+    @mock.patch("opentelemetry.instrumentation.dbapi.instrument_connection")
+    @mock.patch("pymysql.connect")
+    # pylint: disable=unused-argument
+    def test_instrument_connection_dbapi_kwargs_defaults(
+        self,
+        mock_connect,
+        mock_instrument_connection,
+    ):
+        cnx = pymysql.connect(database="test")
+        PyMySQLInstrumentor().instrument_connection(cnx)
+
+        kwargs = mock_instrument_connection.call_args[1]
+        self.assertEqual(kwargs["capture_parameters"], False)
 
     def test_instrument_connection_with_dbapi_sqlcomment_enabled(self):
         mock_connect_module = mock.MagicMock(
@@ -298,6 +314,20 @@ def test_instrument_enable_commenter_dbapi_kwargs(
         self.assertEqual(kwargs["enable_commenter"], True)
         self.assertEqual(kwargs["commenter_options"], {"foo": True})
         self.assertEqual(kwargs["enable_attribute_commenter"], True)
+        self.assertEqual(kwargs["capture_parameters"], False)
+
+    @mock.patch("opentelemetry.instrumentation.dbapi.wrap_connect")
+    @mock.patch("pymysql.connect")
+    # pylint: disable=unused-argument
+    def test_instrument_capture_parameters_dbapi_kwargs(
+        self,
+        mock_connect,
+        mock_wrap_connect,
+    ):
+        PyMySQLInstrumentor()._instrument(capture_parameters=True)
+
+        kwargs = mock_wrap_connect.call_args[1]
+        self.assertEqual(kwargs["capture_parameters"], True)
 
     def test_instrument_with_dbapi_sqlcomment_enabled(
         self,