Hi Xietao,
TNER is an excellent tool for ctDNA error supression, one thing I realized is that we always have a higher coverage in forward strand than the reverse for all healthy samples, is this always the case? I see what TNER does now is to simply add them up, will it affect the estimation of BMER?
Thank you!
Hi Xietao,
TNER is an excellent tool for ctDNA error supression, one thing I realized is that we always have a higher coverage in forward strand than the reverse for all healthy samples, is this always the case? I see what TNER does now is to simply add them up, will it affect the estimation of BMER?
Thank you!