diff --git a/.github/workflows/pre-commit.yml b/.github/workflows/pre-commit.yml
index bce0120..a3ea0fb 100644
--- a/.github/workflows/pre-commit.yml
+++ b/.github/workflows/pre-commit.yml
@@ -36,7 +36,6 @@ jobs:
 
       - name: Install dev dependencies
         run: |
-          set -vxeuo pipefail
           set -vxeuo pipefail
           pixi install --environment=${{ env.python_env }}
           pixi list --environment=${{ env.python_env }}
diff --git a/docs/source/release-history.rst b/docs/source/release-history.rst
index 0b74c0b..aa5ad11 100644
--- a/docs/source/release-history.rst
+++ b/docs/source/release-history.rst
@@ -11,6 +11,11 @@ Removed
 
 - Support for Python 3.10. The minimum supported Python version is now 3.11.
 
+Changed
+-------
+
+- Replace the `httpx` dependency with `httpx2`.
+
 
 v0.0.14 (2026-01-21)
 ====================
diff --git a/pyproject.toml b/pyproject.toml
index 5fd7d63..61d0c75 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -19,7 +19,7 @@ dependencies = [
   "bluesky-queueserver-api",
   "cachetools",
   "fastapi",
-  "httpx",
+  "httpx2",
   "ldap3",
   "orjson",
   "pamela",
@@ -50,7 +50,6 @@ dev = [
   "pytest-xprocess",
   "pytest-split",
   "py",
-  "respx",
   "sphinx",
   "ipython",
   "numpydoc",
diff --git a/src/bluesky_httpserver/authenticators.py b/src/bluesky_httpserver/authenticators.py
index 6f24887..5940ccd 100644
--- a/src/bluesky_httpserver/authenticators.py
+++ b/src/bluesky_httpserver/authenticators.py
@@ -9,7 +9,7 @@
 from datetime import timedelta
 from typing import Any, cast
 
-import httpx
+import httpx2
 from cachetools import TTLCache, cached
 from fastapi import APIRouter, Request
 from fastapi.security import OAuth2, OAuth2AuthorizationCodeBearer
@@ -151,7 +151,7 @@ def __init__(
 
     @functools.cached_property
     def _config_from_oidc_url(self) -> dict[str, Any]:
-        response: httpx.Response = httpx.get(self._well_known_url)
+        response: httpx2.Response = httpx2.get(self._well_known_url)
         response.raise_for_status()
         return response.json()
 
@@ -179,8 +179,8 @@ def token_endpoint(self) -> str:
         return cast(str, self._config_from_oidc_url.get("token_endpoint"))
 
     @functools.cached_property
-    def authorization_endpoint(self) -> httpx.URL:
-        return httpx.URL(cast(str, self._config_from_oidc_url.get("authorization_endpoint")))
+    def authorization_endpoint(self) -> httpx2.URL:
+        return httpx2.URL(cast(str, self._config_from_oidc_url.get("authorization_endpoint")))
 
     @functools.cached_property
     def device_authorization_endpoint(self) -> str:
@@ -192,7 +192,7 @@ def end_session_endpoint(self) -> str:
 
     @cached(TTLCache(maxsize=1, ttl=timedelta(hours=1).total_seconds()))
     def keys(self) -> list[str]:
-        return httpx.get(self.jwks_uri).raise_for_status().json().get("keys", [])
+        return httpx2.get(self.jwks_uri).raise_for_status().json().get("keys", [])
 
     def decode_token(self, id_token: str, access_token: str | None = None) -> dict[str, Any]:
         return jwt.decode(
@@ -419,7 +419,7 @@ async def graph_lookup(self, access_token, user_param):
         """Uses the access token provided in the auth flow to lookup a user parameter"""
         headers = {"Authorization": f"Bearer {access_token}"}
 
-        async with httpx.AsyncClient() as client:
+        async with httpx2.AsyncClient() as client:
             response = await client.get(
                 "https://graph.microsoft.com/v1.0/me",
                 params={"$select": user_param},
@@ -454,10 +454,11 @@ async def get_username_from_graph(self, access_token):
         If no username is found, there are errors in looking up the graphAPI
         username, or whatever it returns None
         """
+        profile = None
         try:
             profile = await self.graph_lookup(access_token, self.graph_username_attribute)
             logger.debug("Graph Profile: %r", profile)
-        except (httpx.HTTPStatusError, httpx.RequestError, ValueError):
+        except (httpx2.HTTPStatusError, httpx2.RequestError, ValueError):
             logger.warning("Graph lookup failed")
         username = None
         if profile:
@@ -566,7 +567,7 @@ async def exchange_code(
     client_secret: str,
     redirect_uri: str,
     extra_scopes: list[str] | None = None,
-) -> httpx.Response:
+) -> httpx2.Response:
     """Exchange an authorization code for tokens at the IdP token endpoint.
 
     Explicitly requests ``openid offline_access`` scopes in the token POST body
@@ -588,7 +589,7 @@ async def exchange_code(
     if extra_scopes:
         scopes.update(extra_scopes)
     auth_value = base64.b64encode(f"{client_id}:{client_secret}".encode()).decode()
-    response = httpx.post(
+    response = httpx2.post(
         url=token_uri,
         data={
             "grant_type": "authorization_code",
diff --git a/src/bluesky_httpserver/authorization/api_access.py b/src/bluesky_httpserver/authorization/api_access.py
index 54263d9..55a3fd1 100644
--- a/src/bluesky_httpserver/authorization/api_access.py
+++ b/src/bluesky_httpserver/authorization/api_access.py
@@ -5,7 +5,7 @@
 import time as ttime
 from collections.abc import Iterable
 
-import httpx
+import httpx2
 import jsonschema
 import yaml
 
@@ -610,7 +610,7 @@ async def update_access_info(self):
         Send a single request to the API server and update locally stored access control info.
         """
         access_api = f"/instrument/{self._instrument.lower()}/qserver/access"
-        async with httpx.AsyncClient(base_url=self._base_url, timeout=self._http_timeout) as client:
+        async with httpx2.AsyncClient(base_url=self._base_url, timeout=self._http_timeout) as client:
             response = await client.get(access_api)
             response.raise_for_status()
             groups = response.json()
diff --git a/src/bluesky_httpserver/tests/conftest.py b/src/bluesky_httpserver/tests/conftest.py
index 5dbe740..a45a540 100644
--- a/src/bluesky_httpserver/tests/conftest.py
+++ b/src/bluesky_httpserver/tests/conftest.py
@@ -2,7 +2,7 @@
 import time as ttime
 from typing import Any
 
-import httpx
+import httpx2
 import pytest
 import requests
 from bluesky_queueserver.manager.comms import zmq_single_request
@@ -12,14 +12,16 @@
 )
 from cryptography.hazmat.primitives.asymmetric import rsa
 from jose.backends import RSAKey
-from respx import MockRouter
 from sqlalchemy import create_engine
 from sqlalchemy.orm import sessionmaker
 from xprocess import ProcessStarter
 
+import bluesky_httpserver.authenticators as authenticators
 import bluesky_httpserver.server as bqss
 from bluesky_httpserver.database.base import Base
 
+from .httpx2_mock import MockRouter
+
 SERVER_ADDRESS = "localhost"
 SERVER_PORT = "60610"
 
@@ -251,16 +253,29 @@ def json_web_keyset(keys: tuple[rsa.RSAPrivateKey, rsa.RSAPublicKey]) -> list[di
 
 @pytest.fixture
 def mock_oidc_server(
-    respx_mock: MockRouter,
+    monkeypatch: pytest.MonkeyPatch,
     oidc_well_known_url: str,
     well_known_response: dict[str, Any],
     json_web_keyset: list[dict[str, Any]],
 ) -> MockRouter:
-    respx_mock.get(oidc_well_known_url).mock(return_value=httpx.Response(httpx.codes.OK, json=well_known_response))
-    respx_mock.get(well_known_response["jwks_uri"]).mock(
-        return_value=httpx.Response(httpx.codes.OK, json={"keys": json_web_keyset})
+    mock_router = MockRouter()
+    mock_router.get(oidc_well_known_url).mock(
+        return_value=httpx2.Response(httpx2.codes.OK, json=well_known_response)
+    )
+    mock_router.get(well_known_response["jwks_uri"]).mock(
+        return_value=httpx2.Response(httpx2.codes.OK, json={"keys": json_web_keyset})
+    )
+    monkeypatch.setattr(
+        authenticators.httpx2,
+        "get",
+        lambda url, **kwargs: mock_router.request("GET", url, **kwargs),
+    )
+    monkeypatch.setattr(
+        authenticators.httpx2,
+        "post",
+        lambda url, **kwargs: mock_router.request("POST", url, **kwargs),
     )
-    return respx_mock
+    return mock_router
 
 
 @pytest.fixture
diff --git a/src/bluesky_httpserver/tests/httpx2_mock.py b/src/bluesky_httpserver/tests/httpx2_mock.py
new file mode 100644
index 0000000..f5ff992
--- /dev/null
+++ b/src/bluesky_httpserver/tests/httpx2_mock.py
@@ -0,0 +1,40 @@
+from dataclasses import dataclass
+
+import httpx2
+
+
+@dataclass
+class Call:
+    request: httpx2.Request
+
+
+class Route:
+    def __init__(self, router: "MockRouter", method: str, url: str):
+        self._router = router
+        self._method = method
+        self._url = url
+
+    def mock(self, *, return_value: httpx2.Response) -> None:
+        self._router._responses[self._method, self._url] = return_value
+
+
+class MockRouter:
+    def __init__(self):
+        self._responses: dict[tuple[str, str], httpx2.Response] = {}
+        self.calls: list[Call] = []
+
+    def get(self, url: str) -> Route:
+        return Route(self, "GET", url)
+
+    def post(self, url: str) -> Route:
+        return Route(self, "POST", url)
+
+    def request(self, method: str, url: str, **kwargs) -> httpx2.Response:
+        request = httpx2.Request(method, url, **kwargs)
+        self.calls.append(Call(request))
+        try:
+            response = self._responses[method, str(request.url)]
+        except KeyError as exc:
+            raise AssertionError(f"Unexpected HTTPX2 request: {method} {request.url}") from exc
+        response.request = request
+        return response
diff --git a/src/bluesky_httpserver/tests/test_authenticators.py b/src/bluesky_httpserver/tests/test_authenticators.py
index 98be453..fc31a4e 100644
--- a/src/bluesky_httpserver/tests/test_authenticators.py
+++ b/src/bluesky_httpserver/tests/test_authenticators.py
@@ -6,18 +6,18 @@
 from typing import Any
 from unittest.mock import MagicMock
 
-import httpx
+import httpx2
 import pytest
 from cryptography.hazmat.primitives.asymmetric import rsa
 from fastapi import HTTPException
 from fastapi.security import SecurityScopes
 from jose import ExpiredSignatureError, jwt
-from respx import MockRouter
 from starlette.datastructures import URL, QueryParams
 from starlette.requests import Request
 
 from bluesky_httpserver import authentication as _auth
 
+from .. import authenticators as authenticators_module
 from ..authenticators import (
     EntraAuthenticator,
     LDAPAuthenticator,
@@ -25,6 +25,7 @@
     ProxiedOIDCAuthenticator,
     UserSessionState,
 )
+from .httpx2_mock import MockRouter
 
 LDAP_TEST_HOST = os.environ.get("QSERVER_TEST_LDAP_HOST", "localhost")
 LDAP_TEST_PORT = int(os.environ.get("QSERVER_TEST_LDAP_PORT", "1389"))
@@ -183,11 +184,40 @@ def mock_decode_token(self, id_token, access_token):
 async def test_proxied_oidc_token_retrieval(oidc_well_known_url: str, mock_oidc_server: MockRouter):
     authenticator = ProxiedOIDCAuthenticator("tiled", "tiled", oidc_well_known_url,
                                              device_flow_client_id="tiled-cli")
-    test_request = httpx.Request("GET", "http://example.com", headers={"Authorization": "bearer FOO"})
+    test_request = httpx2.Request("GET", "http://example.com", headers={"Authorization": "bearer FOO"})
 
     assert "FOO" == await authenticator.oauth2_schema(test_request)
 
 
+@pytest.mark.asyncio
+@pytest.mark.parametrize("status_code, expected", [(200, "alice"), (503, None)])
+async def test_entra_graph_lookup_httpx2(
+    mock_oidc_server, oidc_well_known_url, monkeypatch, status_code, expected
+):
+    authenticator = EntraAuthenticator(
+        audience="tiled",
+        client_id="tiled",
+        well_known_uri=oidc_well_known_url,
+        device_flow_client_id="tiled-cli",
+        graph_username_attribute="userPrincipalName",
+    )
+
+    def handle_request(request):
+        assert request.url == "https://graph.microsoft.com/v1.0/me?%24select=userPrincipalName"
+        assert request.headers["Authorization"] == "Bearer graph-token"
+        return httpx2.Response(status_code, json={"userPrincipalName": "alice"})
+
+    client_class = httpx2.AsyncClient
+    transport = httpx2.MockTransport(handle_request)
+    monkeypatch.setattr(
+        authenticators_module.httpx2,
+        "AsyncClient",
+        lambda **kwargs: client_class(transport=transport, **kwargs),
+    )
+
+    assert await authenticator.get_username_from_graph("graph-token") == expected
+
+
 def create_mock_oidc_request(query_params=None):
     if query_params is None:
         query_params = {}
@@ -225,7 +255,7 @@ async def test_OIDCAuthenticator_mock(
     }
 
     mock_oidc_server.post(well_known_response["token_endpoint"]).mock(
-        return_value=httpx.Response(
+        return_value=httpx2.Response(
             200,
             json={
                 "access_token": "mock-access-token",
@@ -284,7 +314,7 @@ async def test_OIDCAuthenticator_token_exchange_failure(
     well_known_response,
 ):
     mock_oidc_server.post(well_known_response["token_endpoint"]).mock(
-        return_value=httpx.Response(
+        return_value=httpx2.Response(
             400,
             json={
                 "error": "invalid_client",
@@ -476,8 +506,8 @@ def __init__(self):
 
     def copy_with(self, params):
         self.captured_params = params
-        # Return an httpx.URL so RedirectResponse can str() it cleanly.
-        return httpx.URL("https://idp.example.com/authorize").copy_with(params=params)
+        # Return an httpx2.URL so RedirectResponse can str() it cleanly.
+        return httpx2.URL("https://idp.example.com/authorize").copy_with(params=params)
 
 
 @pytest.mark.asyncio
diff --git a/src/bluesky_httpserver/tests/test_httpx2_access.py b/src/bluesky_httpserver/tests/test_httpx2_access.py
new file mode 100644
index 0000000..24a0d6c
--- /dev/null
+++ b/src/bluesky_httpserver/tests/test_httpx2_access.py
@@ -0,0 +1,25 @@
+import httpx2
+import pytest
+
+from bluesky_httpserver.authorization import ServerBasedAPIAccessControl, api_access
+
+
+@pytest.mark.asyncio
+async def test_server_based_access_control_httpx2(monkeypatch):
+    def handle_request(request):
+        assert request.method == "GET"
+        assert request.url == "https://access.example.com/instrument/tst/qserver/access"
+        return httpx2.Response(200, json={"user": {"alice": {"first_name": "Alice"}}})
+
+    client_class = httpx2.AsyncClient
+    transport = httpx2.MockTransport(handle_request)
+    monkeypatch.setattr(
+        api_access.httpx2,
+        "AsyncClient",
+        lambda **kwargs: client_class(transport=transport, **kwargs),
+    )
+
+    manager = ServerBasedAPIAccessControl(instrument="TST", base_url="https://access.example.com")
+    await manager.update_access_info()
+    assert manager.get_user_roles("alice") == {"user"}
+    assert manager.get_displayed_user_name("alice") == 'alice "Alice"'
diff --git a/src/bluesky_httpserver/tests/test_oidc_authenticators.py b/src/bluesky_httpserver/tests/test_oidc_authenticators.py
index 953f87b..9915f08 100644
--- a/src/bluesky_httpserver/tests/test_oidc_authenticators.py
+++ b/src/bluesky_httpserver/tests/test_oidc_authenticators.py
@@ -6,10 +6,11 @@
 import pytest
 from cryptography.hazmat.primitives.asymmetric import rsa
 from jose import ExpiredSignatureError, jwt
-from respx import MockRouter
 
 from bluesky_httpserver.authenticators import OIDCAuthenticator
 
+from .httpx2_mock import MockRouter
+
 
 def create_token(issued: bool, expired: bool) -> dict[str, Any]:
     """Create a test JWT token."""
diff --git a/src/bluesky_httpserver/tests/test_oidc_proxied_authenticators.py b/src/bluesky_httpserver/tests/test_oidc_proxied_authenticators.py
index 044ac76..c5fa289 100644
--- a/src/bluesky_httpserver/tests/test_oidc_proxied_authenticators.py
+++ b/src/bluesky_httpserver/tests/test_oidc_proxied_authenticators.py
@@ -1,11 +1,12 @@
 """Tests for OIDC Authenticator functionality."""
 
-import httpx
+import httpx2
 import pytest
-from respx import MockRouter
 
 from bluesky_httpserver.authenticators import ProxiedOIDCAuthenticator
 
+from .httpx2_mock import MockRouter
+
 
 @pytest.mark.filterwarnings("ignore::DeprecationWarning")
 class TestProxiedOIDCAuthenticator:
@@ -26,7 +27,7 @@ async def test_proxied_oidc_oauth2_schema(
         )
 
         # Create a mock request with Authorization header
-        test_request = httpx.Request(
+        test_request = httpx2.Request(
             "GET",
             "http://example.com/api/test",
             headers={"Authorization": "Bearer TEST_TOKEN"},