diff --git a/python/CMakeLists.txt b/python/CMakeLists.txt
index 99c187507..6c2b12159 100644
--- a/python/CMakeLists.txt
+++ b/python/CMakeLists.txt
@@ -165,11 +165,10 @@ else ()
 endif ()
 
 check_python_module("setuptools" SETUPTOOLS_MODULE_FOUND)
-check_python_module("wheel" WHEEL_MODULE_FOUND)
 check_python_module("cffi" CFFI_MODULE_FOUND)
 
 if (BUILD_MODULE_FOUND AND
-    (ENABLE_PYTHON_ISOLATED OR (SETUPTOOLS_MODULE_FOUND AND WHEEL_MODULE_FOUND AND CFFI_MODULE_FOUND)))
+    (ENABLE_PYTHON_ISOLATED OR (SETUPTOOLS_MODULE_FOUND AND CFFI_MODULE_FOUND)))
   if (BUILD_PYTHON_UNBUNDLED_PKG)
     add_custom_command(OUTPUT .timestamp.dist
       DEPENDS pypkg_src_copied
diff --git a/python/ci_requirements.txt b/python/ci_requirements.txt
index 9b0ec6a7f..2014bc460 100644
--- a/python/ci_requirements.txt
+++ b/python/ci_requirements.txt
@@ -1,7 +1,6 @@
 pip
 build
 setuptools
-wheel
 flake8
 tox>=1.7.2
 cffi>=1.0.0