diff --git a/sigma/backends/sqlite/sqlite.py b/sigma/backends/sqlite/sqlite.py
index 4bac13c..180efe3 100644
--- a/sigma/backends/sqlite/sqlite.py
+++ b/sigma/backends/sqlite/sqlite.py
@@ -13,6 +13,7 @@
 )
 from sigma.types import (
     SigmaCompareExpression,
+    SigmaRegularExpression,
     SigmaString,
     SpecialChars,
     SigmaCIDRExpression,
@@ -477,6 +478,12 @@ def convert_value_str(
         else:
             return converted
 
+    def convert_value_re(
+        self, r: SigmaRegularExpression, state: ConversionState
+    ) -> str:
+        # Doubling single quotes is mandatory: the regex is embedded in a '...' SQL string literal.
+        return super().convert_value_re(r, state).replace("'", "''")
+
     def convert_condition_field_eq_val_str(
         self, cond: ConditionFieldEqualsValueExpression, state: ConversionState
     ) -> Union[str, DeferredQueryExpression]:
diff --git a/tests/test_backend_sqlite.py b/tests/test_backend_sqlite.py
index c69f4f0..eb01a0d 100644
--- a/tests/test_backend_sqlite.py
+++ b/tests/test_backend_sqlite.py
@@ -163,6 +163,27 @@ def test_sqlite_regex_query(sqlite_backend: sqliteBackend):
     )
 
 
+def test_sqlite_regex_query_single_quote(sqlite_backend: sqliteBackend):
+    assert (
+        sqlite_backend.convert(
+            SigmaCollection.from_yaml(
+                """
+            title: Test
+            status: test
+            logsource:
+                category: test_category
+                product: test_product
+            detection:
+                sel:
+                    fieldA|re: it's.exe
+                condition: sel
+        """
+            )
+        )
+        == ["SELECT * FROM <TABLE_NAME> WHERE fieldA REGEXP 'it''s.exe'"]
+    )
+
+
 def test_sqlite_cidr_query(sqlite_backend: sqliteBackend):
     assert (
         sqlite_backend.convert(