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where $\otimes$ is the [Kronecker product](https://en.wikipedia.org/wiki/Kronecker_product).
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@@ -24,7 +24,7 @@ and **parameters** are
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- Maximum likelihood estimation (MLE) and restricted maximum likelihood estimation (REML) of mean parameters `B` and variance component parameters `Σ`
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- Allow constrains in the mean parameters `B`
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- Choice of optimization algorithms: [Fisher scoring](https://books.google.com/books?id=QYqeYTftPNwC&lpg=PP1&pg=PA142#v=onepage&q&f=false) and [minorization-maximization algorithm](http://arxiv.org/abs/1509.07426)
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