From 1d649959f6c5d03d2cfe495a657218d41e6d9104 Mon Sep 17 00:00:00 2001 From: hosseinvk Date: Wed, 12 Aug 2026 00:30:09 +1000 Subject: [PATCH] Remove answers from Enrichment Statistics activity questions Strips the click-to-reveal
answer blocks from the 4 Q&A items in the Activity section, leaving only the questions. --- 03-stats.Rmd | 16 ---------------- 1 file changed, 16 deletions(-) diff --git a/03-stats.Rmd b/03-stats.Rmd index 32eaba1..d1d8a9d 100644 --- a/03-stats.Rmd +++ b/03-stats.Rmd @@ -152,31 +152,15 @@ You can adjust various factors and see their effect on the enrichment p-values. ### **Questions** {- .rationale} 1. If 24 of the 300 differentially expressed genes are annotated with the 500-gene term of interest. Is it significant at p=0.05? -
-Show -No, corrected pval=0.087 -

 

2. What about with a smaller background of 5000 genes (e.g. proteomic datasets)? -
-Show -Even less so - corrected pval=1 -

 

3. Or, testing against a smaller database of terms; 2000 terms instead of 10000? With the original 16000 gene background. -
-Show -Yes, now corrected pval=0.017 -

 

4. 19 out of 200 differentially expressed genes (9.5%), need to hit for a 500-gene term (3.1% of all genes) to be significant at (p=0.048). How many hits would be needed for a more specific 30-gene term? -
-Show -5 hits - 2.5% of the differentially expressed genes vs 0.19% of all genes -
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