diff --git a/pyproject.toml b/pyproject.toml
index 0430b29..4f9bd04 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -11,7 +11,7 @@ license = "Apache-2.0"
 requires-python = ">=3.11"
 authors = [{ name = "assay-gpu contributors" }]
 dependencies = [
-    "cryptography==44.0.3",
+    "cryptography==50.0.1",
     "numpy>=1.26,<3",
     "torch",
     "typer",