Skip to content

Commit e47a555

Browse files
FFroehlichFFroehlich
authored
Fix Isensee_JCB2018 (#138)
* simplify formulation * add parameter priors, fixes #137 * fixup conditions * remove uninformative priors * reexport conditions/measurements from d2d * fixup * fix model * fixup * fix empty rows * remove index from measurement table * update simulated data
1 parent 36c4cf6 commit e47a555

6 files changed

Lines changed: 1567 additions & 1583 deletions

‎Benchmark-Models/Isensee_JCB2018/experimentalCondition_Isensee_JCB2018.tsv‎

Lines changed: 124 additions & 122 deletions
Large diffs are not rendered by default.

‎Benchmark-Models/Isensee_JCB2018/measurementData_Isensee_JCB2018.tsv‎

Lines changed: 687 additions & 687 deletions
Large diffs are not rendered by default.

‎Benchmark-Models/Isensee_JCB2018/model_Isensee_JCB2018.xml‎

Lines changed: 4 additions & 20 deletions
Original file line numberDiff line numberDiff line change
@@ -252,11 +252,7 @@
252252
<apply>
253253
<minus/>
254254
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
255-
<apply>
256-
<minus/>
257-
<cn type="integer"> 60 </cn>
258-
<ci> Rp8_Br_cAMPS_pAB_incubation_time </ci>
259-
</apply>
255+
<ci> Rp8_Br_cAMPS_pAB_incubation_time </ci>
260256
</apply>
261257
<cn type="integer"> 0 </cn>
262258
</apply>
@@ -281,11 +277,7 @@
281277
<apply>
282278
<minus/>
283279
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
284-
<apply>
285-
<minus/>
286-
<cn type="integer"> 60 </cn>
287-
<ci> Rp8_pCPT_cAMPS_pAB_incubation_time </ci>
288-
</apply>
280+
<ci> Rp8_pCPT_cAMPS_pAB_incubation_time </ci>
289281
</apply>
290282
<cn type="integer"> 0 </cn>
291283
</apply>
@@ -310,11 +302,7 @@
310302
<apply>
311303
<minus/>
312304
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
313-
<apply>
314-
<minus/>
315-
<cn type="integer"> 60 </cn>
316-
<ci> Rp_cAMPS_pAB_incubation_time </ci>
317-
</apply>
305+
<ci> Rp_cAMPS_pAB_incubation_time </ci>
318306
</apply>
319307
<cn type="integer"> 0 </cn>
320308
</apply>
@@ -364,11 +352,7 @@
364352
<apply>
365353
<minus/>
366354
<csymbol encoding="text" definitionURL="http://www.sbml.org/sbml/symbols/time"> time </csymbol>
367-
<apply>
368-
<minus/>
369-
<cn type="integer"> 60 </cn>
370-
<ci> fourABnOH_incubation_time </ci>
371-
</apply>
355+
<ci> fourABnOH_incubation_time </ci>
372356
</apply>
373357
<cn type="integer"> 0 </cn>
374358
</apply>

‎Benchmark-Models/Isensee_JCB2018/observables_Isensee_JCB2018.tsv‎

Lines changed: 3 additions & 6 deletions
Original file line numberDiff line numberDiff line change
@@ -1,7 +1,4 @@
11
observableId observableName observableFormula noiseFormula observableTransformation noiseDistribution
2-
pRII_Microscopy_1 observableParameter1_pRII_Microscopy_1 * (observableParameter3_pRII_Microscopy_1 + observableParameter2_pRII_Microscopy_1 * (2 * RIIp_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * observableParameter4_pRII_Microscopy_1 * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (observableParameter4_pRII_Microscopy_1 - observableParameter5_pRII_Microscopy_1 * (observableParameter4_pRII_Microscopy_1 - 1)))) noiseParameter1_pRII_Microscopy_1 * noiseParameter2_pRII_Microscopy_1 * noiseParameter3_pRII_Microscopy_1 lin normal
3-
pRII_Microscopy_3 observableParameter1_pRII_Microscopy_3 * (observableParameter3_pRII_Microscopy_3 + observableParameter2_pRII_Microscopy_3 * (2 * RIIp_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * observableParameter4_pRII_Microscopy_3 * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (observableParameter4_pRII_Microscopy_3 - observableParameter5_pRII_Microscopy_3 * (observableParameter4_pRII_Microscopy_3 - 1)))) noiseParameter1_pRII_Microscopy_3 * noiseParameter2_pRII_Microscopy_3 * noiseParameter3_pRII_Microscopy_3 lin normal
4-
pRII_Microscopy_5 observableParameter1_pRII_Microscopy_5 * (observableParameter3_pRII_Microscopy_5 + observableParameter2_pRII_Microscopy_5 * (2 * RIIp_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * observableParameter4_pRII_Microscopy_5 * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (observableParameter4_pRII_Microscopy_5 - observableParameter5_pRII_Microscopy_5 * (observableParameter4_pRII_Microscopy_5 - 1)))) noiseParameter1_pRII_Microscopy_5 * noiseParameter2_pRII_Microscopy_5 * noiseParameter3_pRII_Microscopy_5 lin normal
5-
pRII_Microscopy_7 observableParameter1_pRII_Microscopy_7 * (observableParameter3_pRII_Microscopy_7 + observableParameter2_pRII_Microscopy_7 * (2 * RIIp_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * observableParameter4_pRII_Microscopy_7 * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (observableParameter4_pRII_Microscopy_7 - observableParameter5_pRII_Microscopy_7 * (observableParameter4_pRII_Microscopy_7 - 1)))) noiseParameter1_pRII_Microscopy_7 * noiseParameter2_pRII_Microscopy_7 * noiseParameter3_pRII_Microscopy_7 lin normal
6-
pRII_Western_1 observableParameter1_pRII_Western_1 * (2 * RIIp_2 + 2 * RIIp_C_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_cAMP_C_2 + 2 * RIIp_Rp_cAMPS_C_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * RIIp_Rp8_Br_cAMPS_C_2 + 2 * RIIp_Sp8_Br_cAMPS_C_2 + 2 * RIIp_Rp8_pCPT_cAMPS_C_2) noiseParameter1_pRII_Western_1 * noiseParameter2_pRII_Western_1 lin normal
7-
Calpha_Microscopy_1 observableParameter2_Calpha_Microscopy_1 + observableParameter1_Calpha_Microscopy_1 * (2 * Csub + 2 * Csub_H89 + 2 * observableParameter3_Calpha_Microscopy_1 * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (observableParameter3_Calpha_Microscopy_1 - observableParameter4_Calpha_Microscopy_1 * (observableParameter3_Calpha_Microscopy_1 - 1))) noiseParameter1_Calpha_Microscopy_1 * noiseParameter2_Calpha_Microscopy_1 lin normal
2+
pRII_Microscopy observableParameter1_pRII_Microscopy * (b_pRII_global + s_pRII_global * (2 * RIIp_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * rel_open * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (rel_open - xi_rel_open * (rel_open - 1)))) noiseParameter1_pRII_Microscopy * s_pRII_global * rho_pRII_Microscopy lin normal
3+
pRII_Western s_pRII_Western * (2 * RIIp_2 + 2 * RIIp_C_2 + 2 * RIIp_cAMP_2 + 2 * RIIp_cAMP_C_2 + 2 * RIIp_Rp_cAMPS_C_2 + 2 * RIIp_Sp8_Br_cAMPS_2 + 2 * RIIp_Rp8_Br_cAMPS_C_2 + 2 * RIIp_Sp8_Br_cAMPS_C_2 + 2 * RIIp_Rp8_pCPT_cAMPS_C_2) s_pRII_Western * rho_pRII_Western lin normal
4+
Calpha_Microscopy observableParameter1_Calpha_Microscopy * (b_Calpha_global + s_Calpha_global * (2 * Csub + 2 * Csub_H89 + 2 * rel_open * (RIIp_C_2 + RIIp_Rp_cAMPS_C_2 + RIIp_Rp8_Br_cAMPS_C_2 + RIIp_Rp8_pCPT_cAMPS_C_2) + 2 * (RIIp_cAMP_C_2 + RIIp_Sp8_Br_cAMPS_C_2) * (rel_open - xi_rel_open * (rel_open - 1)))) s_Calpha_global * rho_Calpha_Microscopy lin normal

‎Benchmark-Models/Isensee_JCB2018/parameters_Isensee_JCB2018.tsv‎

Lines changed: 61 additions & 60 deletions
Original file line numberDiff line numberDiff line change
@@ -1,60 +1,61 @@
1-
parameterId parameterName parameterScale lowerBound upperBound nominalValue estimate
2-
AC_total AC_{total} log10 1E-05 1000 1 0
3-
KD_Fsk KD_{Fsk} log10 1E-05 1000 14.2805171742694 1
4-
KD_H89 KD_{H89} log10 1E-05 1000 0.048074027232332 1
5-
KD_IBMX KD_{IBMX} log10 1E-05 1000 11.960772655864 1
6-
KD_PDE_Csub KD_{PDE,Csub} lin -5 3 0 0
7-
KD_cAMP KD_{cAMP} log10 1E-05 1000 2.85002019924967 1
8-
PDE_total PDE_{total} log10 1E-05 1000 1 0
9-
RII2_total RII2_{total} log10 1E-05 1000 1 0
10-
b_Calpha_global b_{Calpha,global} log10 0.001 1000 101.662732662228 1
11-
b_pRII_global b_{pRII,global} log10 0.001 1000 99.7184671220999 1
12-
kdeg_cAMP kdeg_{cAMP} log10 1E-05 1000 1.00000660182181E-05 1
13-
kdeg_cAMP_free kdeg_{cAMP,free} log10 1E-05 1000 7.38363782272545 1
14-
kdp_AC kdp_{AC} lin -5 3 0 0
15-
kf_Fsk kf_{Fsk} log10 1E-05 1000 999.999958296064 1
16-
kf_H89 kf_{H89} log10 1E-05 1000 0.000742716621349 1
17-
kf_PDE_Csub kf_{PDE,Csub} lin -5 3 0 0
18-
kf_RII_2__RII_C_2 kf_{RII_2,RII_C_2} log10 1E-05 100000 1.26446106685121 1
19-
kf_RII_C_2__RII_2 kf_{RII_C_2,RII_2} log10 1E-05 1000 0.018746739843535 1
20-
kf_RII_C_2__RIIp_C_2 kf_{RII_C_2,RIIp_C_2} log10 1E-05 1000 0.022767932816744 1
21-
kf_RIIp_2__RII_2 kf_{RIIp_2,RII_2} log10 1E-05 1000 0.03230162532087 1
22-
kf_RIIp_C_2__RII_C_2 kf_{RIIp_C_2,RII_C_2} log10 1E-05 1000 0.025703919542656 1
23-
kf_RIIp_cAMP_C_2__RIIp_2 kf_{RIIp_cAMP_C_2,RIIp_2} log10 1E-05 1000 0.105283748414996 1
24-
kf_cAMP kf_{cAMP} log10 1E-05 1000 0.501542412469253 1
25-
ki_IBMX ki_{IBMX} log10 1E-05 1000 999.99999999947 1
26-
ki_Rp8_Br_cAMPS_pAB ki_{Rp8,Br,cAMPS,pAB} log10 1E-05 1000 6.44560005260773 1
27-
ki_Rp8_pCPT_cAMPS_pAB ki_{Rp8,pCPT,cAMPS,pAB} log10 1E-05 1000 9.3898794585472 1
28-
ki_Rp_cAMPS_pAB ki_{Rp,cAMPS,pAB} log10 1E-05 1000 0.016320587381729 1
29-
ki_Sp8_Br_cAMPS_AM ki_{Sp8,Br,cAMPS,AM} log10 1E-05 1000 0.131657936881857 1
30-
kp_AC kp_{AC} lin -5 3 0 0
31-
ks_AC_cAMP ks_{AC,cAMP} log10 1E-05 1000 0.423150583624568 1
32-
rel_open rel_{open} log10 1E-05 1 0.232684484588385 1
33-
s_Calpha_global s_{Calpha,global} log10 1000 3162.27766016838 1758.15501421399 1
34-
s_pRII_JI09_150302_Drg345_343_CycNuc s_{pRII,JI09,150302,Drg345,343,CycNuc} log10 0.001 1000 1.1029976101468 1
35-
s_pRII_JI09_150330_Drg350_348_CycNuc s_{pRII,JI09,150330,Drg350,348,CycNuc} log10 0.001 1000 0.9067516915655 1
36-
s_pRII_JI09_150330_Drg353_351_CycNuc s_{pRII,JI09,150330,Drg353,351,CycNuc} log10 0.001 1000 0.934506349283962 1
37-
s_pRII_JI09_151102_Drg421_418_Age s_{pRII,JI09,151102,Drg421,418,Age} log10 0.001 1000 1.06693094665605 1
38-
s_pRII_Western s_{pRII,Western} log10 0.1 100000 1.14849828435972 1
39-
s_pRII_global s_{pRII,global} log10 1000 3162.27766016838 2206.77137565008 1
40-
rho_Calpha_Microscopy \rho_{Calpha,Microscopy} log10 1E-05 1000 0.049753182233122 1
41-
rho_pRII_Microscopy \rho_{pRII,Microscopy} log10 1E-05 1000 0.040685236621013 1
42-
rho_pRII_Western \rho_{pRII,Western} log10 1E-05 1000 0.099334983213923 1
43-
xi_AC_cAMP_Fsk \xi_{AC_{cAMP,Fsk} log10 1E-05 1000 642.370332155571 1
44-
xi_KD_Rp8_Br_cAMPS \xi_{KD,Rp8,Br,cAMPS} log10 1E-05 100000 0.039962383560766 1
45-
xi_KD_Rp8_pCPT_cAMPS \xi_{KD,Rp8,pCPT,cAMPS} log10 1E-05 100000 0.194212924719718 1
46-
xi_KD_Rp_cAMPS \xi_{KD,Rp,cAMPS} log10 1E-05 100000 0.163047074866588 1
47-
xi_KD_Sp8_Br_cAMPS \xi_{KD,Sp8,Br,cAMPS} log10 1E-05 100000 0.22324026500667 1
48-
xi_b_Rp8_Br_cAMPS \xi_{b,Rp8,Br,cAMPS} log10 1E-05 100000 0.040559301141753 1
49-
xi_b_Rp8_pCPT_cAMPS \xi_{b,Rp8,pCPT,cAMPS} log10 1E-05 100000 0.026684466293791 1
50-
xi_b_Rp_cAMPS \xi_{b,Rp,cAMPS} log10 1E-05 100000 0.603928050380137 1
51-
xi_b_Sp8_Br_cAMPS \xi_{b,Sp8,Br,cAMPS} log10 1E-05 100000 21.6150210996832 1
52-
xi_i_Rp8_Br_cAMPS_pAB \xi_{i,Rp8,Br,cAMPS,pAB} log10 1E-05 1 1 0
53-
xi_i_Rp8_pCPT_cAMPS_pAB \xi_{i,Rp8,pCPT,cAMPS,pAB} log10 1E-05 1 1 0
54-
xi_i_Rp_cAMPS_pAB \xi_{i,Rp,cAMPS,pAB} log10 1E-05 1 1 0
55-
xi_i_Sp8_Br_cAMPS_AM \xi_{i,Sp8,Br,cAMPS,AM} log10 1E-05 1 1 0
56-
xi_kf_RII_2__RII_C_2 \xi_{kf_RII_2,RII_C_2} log10 1E-05 1 0.01893099823943 1
57-
xi_kf_RII_C_2__RII_2 \xi_{kf_RII_C_2,RII_2} log10 1E-05 100000 0.810991675177056 1
58-
xi_pAC \xi_{pAC} log10 0.001 1 1 0
59-
xi_pPDE \xi_{pPDE} log10 1 1000 1 0
60-
xi_rel_open \xi_{rel,open} log10 1E-05 1 0.749424660751357 1
1+
parameterId parameterName parameterScale lowerBound upperBound nominalValue estimate objectivePrior objectivePriorParameters
2+
AC_total AC_{total} log10 1E-05 1000 1 0
3+
KD_Fsk KD_{Fsk} log10 1E-05 1000 14.2805171742694 1 parameterScaleNormal 0.845098;0.2
4+
KD_H89 KD_{H89} log10 1E-05 1000 0.048074027232332 1 parameterScaleNormal -1.31876;0.2
5+
KD_IBMX KD_{IBMX} log10 1E-05 1000 11.960772655864 1 parameterScaleNormal 1.0;0.2
6+
KD_PDE_Csub KD_{PDE,Csub} lin -5 3 0 0
7+
KD_cAMP KD_{cAMP} log10 1E-05 1000 2.85002019924967 1 parameterScaleNormal 0.462398;0.2
8+
PDE_total PDE_{total} log10 1E-05 1000 1 0
9+
RII2_total RII2_{total} log10 1E-05 1000 1 0
10+
b_Calpha_global b_{Calpha,global} log10 0.001 1000 101.662732662228 1 parameterScaleNormal 2;0.1
11+
b_pRII_global b_{pRII,global} log10 0.001 1000 99.7184671220999 1 parameterScaleNormal 2;0.1
12+
kdeg_cAMP kdeg_{cAMP} log10 1E-05 1000 1.00000660182181E-05 1
13+
kdeg_cAMP_free kdeg_{cAMP,free} log10 1E-05 1000 7.38363782272545 1
14+
kdp_AC kdp_{AC} lin -5 3 0 0
15+
kf_Fsk kf_{Fsk} log10 1E-05 1000 999.999958296064 1
16+
kf_H89 kf_{H89} log10 1E-05 1000 0.000742716621349 1
17+
kf_PDE_Csub kf_{PDE,Csub} lin -5 3 0 0
18+
kf_RII_2__RII_C_2 kf_{RII_2,RII_C_2} log10 1E-05 100000 1.26446106685121 1
19+
kf_RII_C_2__RII_2 kf_{RII_C_2,RII_2} log10 1E-05 1000 0.018746739843535 1
20+
kf_RII_C_2__RIIp_C_2 kf_{RII_C_2,RIIp_C_2} log10 1E-05 1000 0.022767932816744 1
21+
kf_RIIp_2__RII_2 kf_{RIIp_2,RII_2} log10 1E-05 1000 0.03230162532087 1
22+
kf_RIIp_C_2__RII_C_2 kf_{RIIp_C_2,RII_C_2} log10 1E-05 1000 0.025703919542656 1
23+
kf_RIIp_cAMP_C_2__RIIp_2 kf_{RIIp_cAMP_C_2,RIIp_2} log10 1E-05 1000 0.105283748414996 1
24+
kf_cAMP kf_{cAMP} log10 1E-05 1000 0.501542412469253 1
25+
ki_IBMX ki_{IBMX} log10 1E-05 1000 999.99999999947 1
26+
ki_Rp8_Br_cAMPS_pAB ki_{Rp8,Br,cAMPS,pAB} log10 1E-05 1000 6.44560005260773 1
27+
ki_Rp8_pCPT_cAMPS_pAB ki_{Rp8,pCPT,cAMPS,pAB} log10 1E-05 1000 9.3898794585472 1
28+
ki_Rp_cAMPS_pAB ki_{Rp,cAMPS,pAB} log10 1E-05 1000 0.016320587381729 1
29+
ki_Sp8_Br_cAMPS_AM ki_{Sp8,Br,cAMPS,AM} log10 1E-05 1000 0.131657936881857 1
30+
kp_AC kp_{AC} lin -5 3 0 0
31+
ks_AC_cAMP ks_{AC,cAMP} log10 1E-05 1000 0.423150583624568 1
32+
rel_open rel_{open} log10 1E-05 1 0.232684484588385 1
33+
s_Calpha_JI09_160201_Drg453_452_CycNuc s_{Calpha,JI09,160201,Drg453,452,CycNuc} log10 1E-5 1000 1 0
34+
s_Calpha_global s_{Calpha,global} log10 1000 3162.27766016838 1758.15501421399 1
35+
s_pRII_JI09_150302_Drg345_343_CycNuc s_{pRII,JI09,150302,Drg345,343,CycNuc} log10 0.001 1000 1.1029976101468 1 parameterScaleNormal 0;0.1
36+
s_pRII_JI09_150330_Drg350_348_CycNuc s_{pRII,JI09,150330,Drg350,348,CycNuc} log10 0.001 1000 0.9067516915655 1 parameterScaleNormal 0;0.1
37+
s_pRII_JI09_150330_Drg353_351_CycNuc s_{pRII,JI09,150330,Drg353,351,CycNuc} log10 0.001 1000 0.934506349283962 1 parameterScaleNormal 0;0.1
38+
s_pRII_JI09_151102_Drg421_418_Age s_{pRII,JI09,151102,Drg421,418,Age} log10 0.001 1000 1.06693094665605 1 parameterScaleNormal 0;0.1
39+
s_pRII_Western s_{pRII,Western} log10 0.1 100000 1.14849828435972 1
40+
s_pRII_global s_{pRII,global} log10 1000 3162.27766016838 2206.77137565008 1
41+
rho_Calpha_Microscopy \rho_{Calpha,Microscopy} log10 1E-05 1000 0.049753182233122 1
42+
rho_pRII_Microscopy \rho_{pRII,Microscopy} log10 1E-05 1000 0.040685236621013 1
43+
rho_pRII_Western \rho_{pRII,Western} log10 1E-05 1000 0.099334983213923 1
44+
xi_AC_cAMP_Fsk \xi_{AC_{cAMP,Fsk} log10 1E-05 1000 642.370332155571 1
45+
xi_KD_Rp8_Br_cAMPS \xi_{KD,Rp8,Br,cAMPS} log10 1E-05 100000 0.039962383560766 1 parameterScaleNormal 0;3
46+
xi_KD_Rp8_pCPT_cAMPS \xi_{KD,Rp8,pCPT,cAMPS} log10 1E-05 100000 0.194212924719718 1 parameterScaleNormal 0;3
47+
xi_KD_Rp_cAMPS \xi_{KD,Rp,cAMPS} log10 1E-05 100000 0.163047074866588 1 parameterScaleNormal 0;3
48+
xi_KD_Sp8_Br_cAMPS \xi_{KD,Sp8,Br,cAMPS} log10 1E-05 100000 0.22324026500667 1 parameterScaleNormal 0;3
49+
xi_b_Rp8_Br_cAMPS \xi_{b,Rp8,Br,cAMPS} log10 1E-05 100000 0.040559301141753 1 parameterScaleNormal 0;3
50+
xi_b_Rp8_pCPT_cAMPS \xi_{b,Rp8,pCPT,cAMPS} log10 1E-05 100000 0.026684466293791 1 parameterScaleNormal 0;3
51+
xi_b_Rp_cAMPS \xi_{b,Rp,cAMPS} log10 1E-05 100000 0.603928050380137 1 parameterScaleNormal 0;3
52+
xi_b_Sp8_Br_cAMPS \xi_{b,Sp8,Br,cAMPS} log10 1E-05 100000 21.6150210996832 1 parameterScaleNormal 0;3
53+
xi_i_Rp8_Br_cAMPS_pAB \xi_{i,Rp8,Br,cAMPS,pAB} log10 1E-05 1 1 0 parameterScaleNormal 0;3
54+
xi_i_Rp8_pCPT_cAMPS_pAB \xi_{i,Rp8,pCPT,cAMPS,pAB} log10 1E-05 1 1 0 parameterScaleNormal 0;3
55+
xi_i_Rp_cAMPS_pAB \xi_{i,Rp,cAMPS,pAB} log10 1E-05 1 1 0 parameterScaleNormal 0;3
56+
xi_i_Sp8_Br_cAMPS_AM \xi_{i,Sp8,Br,cAMPS,AM} log10 1E-05 1 1 0 parameterScaleNormal 0;3
57+
xi_kf_RII_2__RII_C_2 \xi_{kf_RII_2,RII_C_2} log10 1E-05 1 0.01893099823943 1 parameterScaleNormal -1.74244;0.1
58+
xi_kf_RII_C_2__RII_2 \xi_{kf_RII_C_2,RII_2} log10 1E-05 100000 0.810991675177056 1 parameterScaleNormal -0.0621479;0.1
59+
xi_pAC \xi_{pAC} log10 0.001 1 1 0 parameterScaleNormal 0;3
60+
xi_pPDE \xi_{pPDE} log10 1 1000 1 0 parameterScaleNormal 0.39794;3
61+
xi_rel_open \xi_{rel,open} log10 1E-05 1 0.749424660751357 1

0 commit comments

Comments
 (0)